Active Ingredient: Doxycycline
If you have severe or persistent diarrhea, tell your doctor. Tell your doctor right away if you have these symptoms. Women of childbearing age who are overweight have a higher risk of this condition.
Severe skin reaction warning: This drug can cause serious skin reactions. These include conditions called Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms DRESS.
Symptoms can include blisters, peeling skin, and a rash of small purple spots. If you have any of these symptoms, stop taking this drug and call your doctor right away.
What is doxycycline? Generic drugs usually cost less. Doxycycline tablets come in immediate-release and delayed-release forms.
Doxycycline also comes in two other oral forms: capsule and solution. Ask your doctor if this drug is right for you.
For people with a history of intracranial hypertension: You have a higher risk of high blood pressure inside of your skull from this drug. Warnings for other groups For pregnant women: There are no adequate studies on the use of doxycycline in pregnant women.
Ask your doctor to tell you about the specific risk to the pregnancy. Call your doctor right away if you become pregnant while taking this drug.
Talk to your doctor if you breastfeed your child. This can cause your body to process drugs more slowly.
As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. This drug should not be used in children who are 8 years of age or younger unless the potential benefit outweighs the risk.
In these children, its use is recommended for the treatment of severe or life-threatening conditions such as anthrax or Rocky Mountain spotted fever, and when no other treatments are available or have been shown to work. Doxycycline has also been used in several animal models of neovascularisation or tumorogenesis with very promising results —.
Recently, we developed a mouse model of pterygium and demonstrated that oral doxycycline drastically reduced pterygium lesions in this experimental model. In addition, treatment of short-term pterygium cultures with doxycycline for 24 h resulted in a sharp change in expression of mitochondrial genes, activation of the endoplasmic reticulum stress response and profound changes in the expression of extracellular matrix proteins, adhesion molecules, and growth factors.
The very affordable economic value of this drug together with its safety profile made doxycycline a promising therapeutic candidate for the treatment of pterygium and other ocular diseases.