Active Ingredient: Gabapentin
How should I take Neurontin? Take Neurontin exactly as prescribed by your doctor. Follow all directions on your prescription label.
Do not take this medicine in larger or smaller amounts or for longer than recommended. Neurontin can be taken with or without food.
If you break a Neurontin tablet and take only half of it, take the other half at your next dose. Any tablet that has been broken should be used as soon as possible or within a few days.
Swallow the capsule or tablet whole and do not crush, chew, break, or open it. Measure liquid medicine carefully.
A total of 8 studies were included in the systematic review and 6 studies for meta-analysis evaluating pain relief as the primary outcomes. Gabapentin demonstrated minimal improvement in pain compared with placebo but was accompanied by significant increases in adverse effects, including dizziness, fatigue, mental difficulties, and visual disturbances.
In the cross-over trial by Bordeleau et al, 27 a higher portion of patients preferred venlafaxine over gabapentin due to greater reduction in hot flash severity and frequency with fewer adverse effects and less frequent dosing.
Saadati et al 28 found gabapentin to produce significantly greater reductions of hot flash frequency, severity, and duration as compared with placebo after 3 months of therapy, with these results corroborated by Pinkerton et al 29 in a larger trial of 600 participants.
Her symptoms resolved with hemodialysis.
The effects of chronically elevated levels in nondialysis-dependent patients with chronic renal impairment have also been demonstrated.