Active Ingredient: Orlistat
Xenical is a weight loss dieting aid which prevents around a third of consumed fat being absorbed into the body.
Each capsule contains 120 mg of the active ingredient orlistat.
The other ingredients are microcrystalline cellulose E 460, sodium starch glycolate type A, povidone E 1201, sodium laurilsulfate and talc.
The capsule shell consists of gelatine, indigo carmine E 132, titanium dioxide E 171 and edible printing ink.
Xenical is a weight loss medication used to assist weight loss in obese patients with a BMI above 30, or for those with associated risk factors such as diabetes, heart disease, high blood pressure or high cholesterol and a BMI above 28.
Xenical works to stop the absorption of fat from your food. By reducing the fat that is absorbed from your diet Xenical can help you lose weight more easily.
What is the difference between Xenical and Orlistat? Waist circumferences greater than 94 cm in men and greater than 80 cm in women, and waist-to-hip ratios greater than 0. Familial Trends.
Studies of twins have clearly established a genetic basis of obesity.
However, a specific gene defect is yet to be isolated in humans. Thrifty Gene. Neel's theory is based on the fact that for thousands of years, populations who relied on farming, hunting, and fishing for food such as the Pima Indians experienced alternating periods of feast and famine.
To adapt to these extreme changes in caloric needs, these people developed a thrifty gene that allowed them to store fat during times of plenty so that they would not starve during times of famine.
This gene was helpful as long as there were periods of famine.
But once these populations adopted the typical Western lifestyle, with less physical activity, a high fat diet, and access to a constant supply of calories, this gene began to work against them, continuing to store calories in preparation for famine.
Racial Factors. Obesity is more prevalent in African American populations in the United States, especially in non-Hispanic black women.
Obesity is frequently a clinical manifestation in a variety of neurological disorders. It is attributed to damage to the ventromedial portion of the hypothalamus. Damage to the hypothalamus is documented to induce hyperactivation of endocannabinoid system leading to hyperphagia and hyperinsulinemia, both of which promote weight gain resulting in obesity.
Cushing's syndrome in adults causes characteristic centripetal obesity involving the face, neck, trunk, and abdomen.
Several drugs have been implicated in induction of obesity. Metabolic Process.
Some researchers believe that there is increased fat synthesis due to preferential shunting of nutrients into lipid-producing pathways. Ghrelin is a hormone produced by the stomach that stimulates appetite, and leptin is a hormone produced by the adipocytes that induces satiety.
It has been proposed that obese individuals are resistant to the action of leptin because high levels of leptin and low levels of ghrelin are well documented in obesity.
Overeating in adult life causes increased fat cell size hypertrophic obesity whereas overeating in early life leads to childhood obesity of hyperplastic variety increased fat cell number.
A direct correlation is established between total daily energy expenditure and fat free mass.
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