Active Ingredient: Orlistat
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In the absence of rigorous supervision of food intake, many PWS patients weigh more than twice their ideal body weight. The growing understanding of the natural history of PWS has more recently identified seven successive nutritional and eating behavior phases, proceeding from poor feeding and failure to thrive Phase 1 a, to normal eating without Phase 1 b or with obesity Phase 2 a, to increased interest for food and weight gain Phase 2 b, and to hyperphagia and life-threatening obesity Phase 3.
Patients with PWS typically display aggressive and obsessive food seeking, food storage, foraging, and hoarding and stealing of either food or money to buy food, which are viewed by some physicians as part of a broader abnormal behavior. All of these represent a lifelong source of distress for patients and families and negatively affect social adaptation, occupational performance, and quality of life.
PWS individuals are forced to live a dependent life, requiring strict control over access to food and continuous care and supervision.
The majority of the common side effects experienced with Xenical are related to the way it works in your digestive system.
These side effects are usually mild, occur at the beginning of treatment, and particularly after high fat meals. Normally these symptoms will subside as you continue treatment and follow your recommended diet. Taking Xenical makes it more difficult for your body to absorb certain vitamins so it is important to take multivitamin supplements of vitamins A, E, and K once a day at least 2 hours before or after taking Xenical, such as at bedtime.